Nobuya Ishibashi Selected Research

doxifluridine

11/2007	Oral fluoropyrimidines may not reduce the risk of postoperative recurrence in colorectal cancer associated with mesenteric lymph node metastasis.
7/2007	Significance of thymidine phosphorylase in metronomic chemotherapy using CPT-11 and doxifluridine for advanced colorectal carcinoma.
5/2006	The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.
1/2006	Upregulation of thymidine phosphorylase in rectal cancer tissues by mitomycin C.
1/2005	The benefit of post-operative adjuvant chemotherapy using oral fluoropyrimidines in rectal cancer.

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Nobuya Ishibashi Research Topics

Disease

15	Colorectal Neoplasms (Colorectal Cancer) 11/2016 - 01/2005
12	Neoplasms (Cancer) 02/2015 - 10/2003
8	Neoplasm Metastasis (Metastasis) 01/2014 - 01/2005
4	Colonic Neoplasms (Colon Cancer) 07/2011 - 01/2005
3	Carcinoma (Carcinomatosis) 02/2015 - 09/2008
3	Rectal Neoplasms (Rectal Cancer) 05/2012 - 01/2005
2	Hypoxia (Hypoxemia) 11/2016 - 02/2002
2	Stomatitis 02/2016 - 04/2012
2	Neutropenia 04/2012 - 04/2010
2	Ulcerative Colitis 08/2010 - 01/2004
2	Stroke (Strokes) 12/2002 - 02/2002
1	Fever (Fevers) 11/2016
1	Dyspnea (Shortness of Breath) 11/2016
1	Interstitial Lung Diseases (Interstitial Lung Disease) 11/2016
1	Lung Diseases (Lung Disease) 11/2016
1	Pain (Aches) 05/2015
1	Polyps 05/2015
1	Gallstones (Gallstone) 05/2015
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 02/2015
1	Acquired Immunodeficiency Syndrome (AIDS) 07/2013
1	Starvation 01/2013
1	Malnutrition (Nutritional Deficiencies) 01/2013
1	Hepatocellular Carcinoma (Hepatoma) 01/2013
1	Neoplasm Micrometastasis 11/2012
1	Carcinogenesis 08/2010
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 04/2010
1	Diarrhea 04/2010
1	Leukopenia 04/2010
1	Drug Eruptions (Drug Eruption) 04/2010
1	Anorexia 04/2010
1	Erythema Multiforme 04/2010
1	Erythema 04/2010
1	Thrombocytopenia (Thrombopenia) 04/2010
1	Necrosis 10/2006
1	Sepsis (Septicemia) 10/2006
1	Lymphatic Metastasis 05/2006
1	Avitaminosis (Vitamin Deficiency) 01/2006
1	Hyperplasia 01/2004

Drug/Important Bio-Agent (IBA)

6	Irinotecan (Camptosar)FDA LinkGeneric 01/2013 - 07/2007
5	doxifluridineIBA 11/2007 - 01/2005
4	Fluorouracil (Carac)FDA LinkGeneric 02/2016 - 04/2010
3	CytokinesIBA 01/2014 - 10/2006
3	Messenger RNA (mRNA)IBA 01/2013 - 04/2002
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2006 - 02/2002
2	Pharmaceutical PreparationsIBA 11/2016 - 04/2010
2	Methylprednisolone FDA LinkGeneric 01/2014 - 04/2002
2	Bevacizumab (Avastin)FDA Link 07/2011 - 09/2008
2	Proteins (Proteins, Gene)FDA Link 08/2010 - 01/2006
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 04/2010 - 01/2006
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2008 - 05/2006
2	Thymidine PhosphorylaseIBA 07/2007 - 01/2006
2	Glutathione PeroxidaseIBA 12/2002 - 02/2002
1	trifluridine tipiracil drug combinationIBA 11/2016
1	Amino Acids FDA Link 02/2016
1	regorafenibIBA 02/2015
1	urinastatin (MR 20)IBA 01/2014
1	AntioxidantsIBA 11/2013
1	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2013
1	CorticosteroneIBA 01/2013
1	Tumor Biomarkers (Tumor Markers)IBA 05/2012
1	Cetuximab (Erbitux)FDA Link 05/2012
1	Biomarkers (Surrogate Marker)IBA 07/2011
1	Claudin-1IBA 08/2010
1	CateninsIBA 08/2010
1	SteroidsIBA 04/2010
1	AntigensIBA 01/2009
1	Indicators and Reagents (Reagents)IBA 01/2009
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 09/2008
1	Cytotoxins (Cytolysins)IBA 09/2008
1	UracilIBA 11/2007
1	InterleukinsIBA 10/2006
1	Proteasome InhibitorsIBA 10/2006
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 10/2006
1	Proteasome Endopeptidase Complex (Proteasome)IBA 10/2006
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2006
1	Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA 01/2006
1	VitaminsIBA 01/2006
1	Capecitabine (Xeloda)FDA Link 01/2006
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2004
1	Polytetrafluoroethylene (Teflon)FDA Link 01/2004
1	Angiotensin IIIBA 01/2004

Therapy/Procedure

13	Drug Therapy (Chemotherapy) 11/2016 - 01/2005
11	Therapeutics 11/2016 - 10/2003
6	Adjuvant Chemotherapy 01/2009 - 01/2005
3	Laparotomy 01/2014 - 04/2002
2	Drug Tapering 02/2016 - 04/2012
2	Hepatectomy 07/2013 - 03/2008
2	Lymph Node Excision (Lymph Node Dissection) 05/2006 - 01/2005
1	Cholecystectomy 05/2015
1	Analgesia 05/2015
1	Laparoscopic Cholecystectomy 05/2015
1	Esophagectomy 11/2013
1	Enteral Nutrition (Feeding, Tube) 11/2013
1	Radiofrequency Ablation 11/2012
1	Intraperitoneal Injections 07/2011
1	Chemoradiotherapy 04/2010
1	Radiotherapy 04/2010
1	Punctures 10/2006
1	Ligation 10/2006
1	Colectomy 01/2004